Journal Articles

Journal Articles (1989 – present) 

• Sun D, Hadjiiski LM, Gormley JR, Chan HP, Caoili EM, Cohan RH, Alva A, Bruno G, Mihalcea R, Zhou C, Gulani V. Outcomes prediction using multi-modal information: Integrating large language model extracted clinical information and image analysis. Cancers 2024; 16(13): 2402. PMID: 39001463, PMCID: PMC11240460. DOI: 10.3390/cancers16132402

• Wang Y, Zhou C, Ying L, Chan HP, Lee E, Chughtai A, Hadjiiski LM, Kazerooni EA. Enhancing early lung cancer diagnosis: Predicting lung nodule progression in follow-up low-dose CT scans with deep generative model. Cancers 2024; 16(12): 2229. PMID: 38927934, PMCID:  PMC11201561. DOI: 10.3390/cancers16122229

• Samala R, Drukker K, Shukla-Dave A, Chan HP, Sahiner B, Petrick N, Greenspan H, Mahmood U, Summers RM, Tourassi G, Deserno TM, Regge D, Näppi JJ, Yoshida H, Huo Z, Chen Q, Vergara D, Cha K, Mazurchuk R, Grizzard KT, Huisman H, Morra L, Suzuki K, Armato III SG, Hadjiiski L. AI and machine learning in medical imaging: key points from development to translation. British Journal of Radiology|Artificial Intelligence 2024; 1(1): ubae006. (Invited Opinion paper).  PMID: 38828430, PMCID: PMC11140849. DOI: 10.1093/bjrai/ubae006

• Wang Y, Zhou C, Ying L, Lee E, Chan HP, Chughtai A, Hadjiiski LM, Kazerooni EA.  Leverage serial low-dose CT scans in radiomic-based reinforcement learning for improvement of early diagnosis of lung cancer at baseline screening. Radiology: Cardiothoracic Imaging. 2024; 6(3): e230196. PMID: 38752718, PMCID: PMC11211947. DOI: 10.1148/ryct.230196

• Gao M, Fessler JA, Chan HP.  X-ray Source Motion Blur Modeling and Deblurring with Generative Diffusion for Digital Breast Tomosynthesis. Physics in Medicine and biology 2024; 69: 115003. PMID: 38640913, PMCID: PMC11103667. DOI: 10.1088/1361-6560/ad40f8

• Mahmood U, Shukla-Dave A, Chan HP, Drukker K, Samala R, Chen Q, Vergara D, Greenspan H, Petrick N, Sahiner B, Huo Z, Summers RM, Cha K, Tourassi G, Deserno TM, Grizzard KT, Näppi JJ, Yoshida H, Regge D, Mazurchuk R, Armato III SG, Hadjiiski L. AI in Medicine: Mitigating Risks and Maximizing Benefits via Quality Assurance, Quality Control, and Acceptance Testing.  British Journal of Radiology|Artificial Intelligence 2024; 1(1): ubae003. (Invited Opinion paper) PMID: 38476957, PMCID: PMC10928809. DOI: 10.1093/bjrai/ubae003

• Sobiecki A, Hadjiiski LM, Chan HP, Samala RK, Zhou C, Stojanovska J, Agarwal PP. Detection of Severe Lung Infection on Chest Radiographs of COVID-19 Patients: Robustness of AI models across multi-institutional data.  Diagnostics 2024; 14(3): 341. PMID: 38337857, PMCID: PMC10855789. DOI: 10.3390/diagnostics14030341

•  Chan HP.  Potential of AI-assisted analysis of mammograms for extensive intraductal component in invasive breast cancer. European Radiology 2024; 34:2590-2592. PMID: 37971682. DOI: 10.1007/s00330-023-10449-x

• Gao M, Fessler JA, Chan HP.  Model-based Deep CNN-Regularized Reconstruction for Digital Breast Tomosynthesis with a Task-based CNN Image Assessment Approach. Physics in Medicine and Biology 2023; 68: 245024. PMID: 37988758, PMCID: PMC10719554. DOI: 10.1088/1361-6560/ad0eb4

• Sun D, Hadjiiski L, Gormley J, Chan HP, Caoili EM, Cohan RH, Alva A, Gulani V, Zhou C. Survival Prediction of Patients with Bladder Cancer after Cystectomy Based on Clinical, Radiomics, and Deep-Learning Descriptors. Cancers 2023; 15(17):4372. PMID: 37686647, PMCID: PMC10486459. DOI: 10.3390/cancers15174372

• Chan HP, Helvie MA, Gao M, Hadjiiski LM, Zhou C, Garver K, Klein KA, McLaughlin C, Neal CH, Oudsema R, Rahman WT, Roubidoux MA. Deep learning denoising of digital breast tomosynthesis: Observer performance study of the effect on detection of microcalcifications in breast phantom images. Medical Physics 2023; 50: 6177-6189. PMID: 37145996, PMCID: PMC10592580. DOI: 10.1002/mp.16439

• Kushwaha A, Mourad RF, Heist K, Tariq H, Chan HP, Ross BD, Chenevert TL, Malyarenko D, Hadjiiski LM. Improved repeatability of mouse tibia volume segmentation in murine myelofibrosis model using deep learning. Tomography 2023; 9:589-602. PMID: 36961007, PMCID: PMC10037585. DOI: 10.3390/tomography9020048

• Hadjiiski L, Cha K, Chan HP, Drukker K, Morra L, Näppi JJ, Sahiner B, Yoshida H, Chen Q, Deserno TM, Greenspan H, Huisman H, Huo Z, Mazurchuk R, Petrick N, Regge D, Samala R, Summers RM, Suzuki K, Tourassi G, Vergara D, Armato III SG.  AAPM task group report 273: Recommendations on best practices for AI and machine learning for computer-aided diagnosis in medical imaging. Medical Physics 2023; 50: e1-e24. PMID: 36565447. DOI: 10.1002/mp.16188

• Vasey B, Nagendran M, Campbell B, et al. Reporting guideline for the early-stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI. Nature Medicine 2022; 28: 924–933.  PMID: 35585198; BMJ 2022; 377: e070904. PMID: 35584845, PMCID: PMC9116198. DOI: 10.1136/bmj-2022-070904

•  Wang Y, Zhou C, Chan HP, Hadjiiski LM, Chughtai A, Kazerooni EA.  Hybrid U-Net based deep-learning model for volume segmentation of lung nodules in CT images. Medical Physics 2022; 49(11): 7287-7302. PMID: 35717560, PMCID: PMC10087884. DOI: 10.1002/mp.15810

• Zhou C, Chan HP, Hadjiski LM, Chughtai A. Recursive training strategy for a U-Net deep learning network for segmentation of pathology nuclei with incomplete annotation. IEEE Access 2022;10: 49337-49346. PMID: 35665366, PMCID: PMC9161776. DOI: 10.1109/access.2022.3172958

• Sun D, Hadjiiski LM, Alva A, Zakharia Y, Joshi M, Chan HP, Garje R, Pomerantz L, Elhag D, Cohan RH, Caoili EM, Wesley TK, Cha KH, Kirova-Nedyalkova G, Davenport MS, Shankar PR, Francis IR, Shampain K, Meyer N, Barkmeier D, Woolen SA, Palmbos PL, Weizer AZ, Samala RK, Zhou C, Matuszak M. Computerized decision support for bladder cancer treatment response assessment in CT urography: Effect on diagnostic accuracy in multi-institutional multi-specialty study. Tomography 2022; 8: 644-656. PMID: 35314631, PMCID: PMC8938803. DOI: 10.3390/tomography8020054

• El Naqa I, Boone JM, Benedict SH, Goodsitt MM, Chan HP, Drukker K, Hadjiiski L, Ruan D, Sahiner B.  AI in Medical Physics: Guidelines for Publication. Medical Physics 2021; 48: 4711-4714. (Editorial). PMID: 34545957. DOI: 10.1002/mp.15170

• Chan HP, Helvie MA. Using single-view wide-angle DBT with AI for breast cancer screening. Radiology 2021; 300(3): 537-538. (Invited Editorial). PMID: 34227888. DOI: 10.1148/radiol.2021211203

• Chan HP. Promise and potential pitfalls: re-creating images or generating new images for AI modeling. Radiology: Artificial Intelligence 2021: 3(4); e210102. 6/2021. (Invited Commentary) PMID: 34350415, PMCID: PMC8328104. DOI: 10.1148/ryai.2021210102

• Gao M, Fessler JA, Chan HP.  Deep convolutional neural network with adversarial training for denoising digital breast tomosynthesis images.  IEEE Trans. Medical Imaging 2021; 40: 1805-1816.  PMID: 33729933, PMCID: PMC8274391  DOI: 10.1109/TMI.2021.3066896

• Samala RK, Chan HP, Hadjiiski LM, Helvie MA.  Risks of feature leakage and sample size dependencies in deep feature extraction for breast mass classification. Medical Physics 2021; 48(6): 2827-2837.  PMID: 33368376, PMCID: PMC8601676.  DOI: 10.1002/mp.14678 

• Chan HP, Helvie MA, Klein KA, McLaughlin C, Neal CH, Oudsema R, Rahman WT, Roubidoux MA, Hadjiiski LM, Zhou C, Samala RK. Effect of dose level on radiologists’ detection of microcalcifications in digital breast tomosynthesis: An observer study with breast phantoms. Academic Radiology. 2022; 29 Supplement 1, Special Issue: Breast Imaging. S42-S49. PMID: 32950384. DOI: 10.1016/j.acra.2020.07.038

• Ikejimba LC, Salad J, Graff CG, Goodsitt MM, Chan HP, Huang H, Zhao W, Ghammraoui B, Lo JY, Glick SJ. Assessment of task-based performance from five clinical DBT systems using an anthropomorphic breast phantom. Medical Physics 2021; 48: 1026-1038. PMID: 33128288. DOI: 10.1002/mp.14568

• Woolen S, Virkud A, Hadjiiski L, Cha K, Chan HP, Swiecicki P, Worden F, Srinivasan A. Prediction of disease free survival in laryngeal and hypopharyngeal cancers using CT perfusion and radiomic features. Tomography 2021; 7: 10-19. PMID:33681460, PMCID: PMC7934704. DOI: 10.3390/tomography7010002

• Pujara AC, Joe AI, Patterson SK, Neal CH, Noroozian M, Chan HP, Helvie MA, Maturen K. Digital breast tomosynthesis slab thickness: Impact on reader performance and interpretation time. Radiology. 2020; 297: 534-542. PMID: 33021891. DOI: 10.1148/radiol.2020192805

• Zhou C, Chan HP, Chughtai AR, Hadjiiski LM, Wei J, Kazerooni EA. Pathologic categorization of lung nodules: radiomic descriptors of CT attenuation distribution patterns of solid and subsolid nodules in LDCT.  European J Radiology 2020; 129: 109106. PMID: 32526671. DOI: 10.1016/j.ejrad.2020.109106

• Hadjiiski LM, Cha KH, Cohan RH, Chan HP, Caoili EM, Davenport MS, Samala RK, Weizer AZ, Alva A, Kirova-Nedyalkova G, Shampain K, Meyer N, Barkmeier D, Woolen SA, Shankar PR, Francis IR, Palmbos PL. Intraobserver Variability in Bladder Cancer Treatment Response Assessment with and without Computerized Decision Support. Tomography 2020; 6: 194-202.PMID:32548296, PMCID: PMC7289252. DOI: 10.18383/j.tom.2020.00013 

• McNitt-Gray M, Napel S, Jaggi A, Mattonen SA, Hadjiiski L, Muzi M, Goldgof D, Balagurunathan Y, Pierce II LA, Kinahan PE, Jones EF, Nguyen A, Virkud A, Chan HP, Emamineja N, Wahi-Anwar M, Daly M, Abdalah M, Yang H, Lu L, Lv W, Rahmim A, Gastounioti A, Pati S, Bakas S, Kontos D, Zhao B, Kalpathy-Cramer J, Farahani K. Standardization in Quantitative Imaging: A Multicenter Comparison of Radiomic Features from Different Software Packages on Digital Reference Objects and Patient Datasets. Tomography 2020; 6: 118-128. PMID:32548288, PMCID: PMC7289262. DOI: 10.18383/j.tom.2019.00031

• Chan HP, Hadjiiski LM, Samala RK.  Computer-Aided Diagnosis in the Era of Deep Learning. Medical Physics 2020; 47: e218-e227. (Invited review). PMID: 32418340. DOI: 10.1002/mp.13764

• Samala RK, Chan HP, Hadjiiski LM, Helvie MA. Richter C.  Generalization Error Analysis for Deep Convolutional Neural Network with Transfer Learning in Breast Cancer Diagnosis. Physics in Medicine and Biology 2020; 65: 105002. PMID:32208369. DOI: 10.1088/1361-6560/ab82e8

• Chan HP, Samala RK, Hadjiiski LM.  CAD and AI for Breast Cancer – Recent Development and Challenges.  British Journal of Radiology 2020; 93: 20190580.  PMID:31742424. DOI: 10.1259/bjr.20190580

• Zheng J, Fessler JA, Chan HP. Effect of Source Blur on Digital Breast Tomosynthesis Reconstruction. Medical Physics 2019; 46: 5572-5592. PMID:31494953, PMCID: PMC6899200. DOI: 10.1002/mp.13801

• Zhou C, Chan HP, Chughtai AR, Patel S, Kuriakose J, Hadjiiski LM, Wei J, Kazerooni EA.  Variabilities in reference standard by radiologists and performance assessment in detection of pulmonary embolism CT pulmonary angiography. Journal of Digital Imaging 2019; 32: 1089-1096. PMID:31073815, PMCID: PMC6841909. DOI: 10.1007/s10278-019-00228-w

• Cha KH, Hadjiiski LM, Cohan RH, Chan HP, Caoili EM, Davenport M, Samala RK, Weizer AZ, Alva A, Kirova-Nedyalkova G, Shampain K, Meyer N, Barkmeier D, Woolen S, Shankar PR, Francis I, Palmbos P. Diagnostic accuracy of CT for prediction of bladder cancer treatment response assessment with and without computerized decision support. Academic Radiology 2019; 26: 1137-1145. PMID: 30424999, PMCID: PMC6510656. DOI: 10.1016/j.acra.2018.10.010

• Sayyouh M, Hadjiiski LM, Chan HP, Agarwal P.  Lung Nodule: Imaging Features and Evaluation in The Age of Machine Learning. Current Pulmonology Reports 2019; 8: 86-95 (Invited review). DOI:10.1007/s13665-019-00229-8 

• Ma X, Wei J, Zhou C, Helvie MA, Chan HP, Hadjiiski LM, Lu Y. Automated Pectoral Muscle Identification on MLO-view Mammograms: Comparison of Deep Neural Network to Conventional Computer Vision Approach. Medical Physics 2019; 46: 2103-2114. PMID: 30771257. DOI: 10.1002/mp.13451

• Ma X, Hadjiiski L, Wei J, Chan HP, Cha KH, Cohan RH, Caoili EM, Samala RK, Zhou C, Lu Y. U-Net-based Deep-Learning Bladder Segmentation in CT Urography. Medical Physics 2019; 46: 1752-1765.  PMID:30734932, PMCID: PMC6453730. DOI: 10.1002/mp.13438

• Wu E, Hadjiiski LM, Samala RK, Chan HP, Cha KH, Richter C, Cohan RH, Caoili EM, Paramagul C, Alva A, Weizer A. Deep Learning Approach for Assessment of Bladder Cancer Treatment Response. Tomography 2019; 5: 201-208. PMID:30854458, PMCID: PMC6403041. DOI: 10.18383/j.tom.2018.00036

• Samala RK, Chan HP, Hadjiiski LM, Helvie MA. Richter C, Cha K. Breast Cancer Diagnosis in Digital Breast Tomosynthesis: Effects of Training Sample Size on Multi-Stage Transfer Learning using Deep Neural Nets. IEEE Trans Medical Imaging 2019; 38: 686-696. PMID:31622238, PMCID: PMC6812655. DOI: 10.1109/TMI.2018.2870343

• Wei J, Chan HP, Helvie MA, Roubidoux MA, Neal CH, Lu Y, Hadjiiski LM, Zhou C. Synthesizing Mammogram from Digital Breast Tomosynthesis. Physics in Medicine and Biology 2019; 64: 045011 (11pp).  PMID:30625429, PMCID: PMC6438841. DOI: 10.1088/1361-6560/aafcda

• Gordon MN, Hadjiiski LM, Cha KH, Samala RK, Chan HP, Cohan RH, Caoili EM. Deep-Learning Convolutional Neural Network: Inner and Outer Bladder Wall Segmentation in CT Urography. Medical Physics 2019; 46: 634-648. PMID:30520055, PMCID: PMC6367014. DOI: 10.1002/mp.13326

• Chan HP, Helvie MA. Deep Learning for Mammographic Breast Density Assessment and Beyond. Radiology 2019; 290: 59-60. (Invited Editorial). PMID: 30325286. DOI: 10.1148/radiol.2018182116

• Alvarez R, Ridelman E, Rizk N, White MS, Zhou C, Chan HP, Varban OA, Helvie MA, and Seeley RJ. Assessment of Mammographic Breast Density After Sleeve Gastrectomy. Surgery for Obesity and Related Diseases (SOARD) 2018; 14: 1643-1651. PMID:30195656, PMCID: PMC6289637. DOI: 10.1016/j.soard.2018.07.024

• Samala RK, Chan HP, Hadjiiski LM, Helvie MA. Richter C, Cha K. Evolutionary Pruning of Transfer Learned Deep Convolutional Neural Network for Breast Cancer Diagnosis in Digital Breast Tomosynthesis. Physics in Medicine and Biology 2018; 63: 095005. PMCID: PMC5967610. DOI: 10.1088/1361-6560/aabb5b

• Marentis TC, Davenport MS, Dillman JR, Sanchez R, Kelly AM, Cronin PP, DeFreitas MR, Hadjiiski L, Chan HP. Interrater agreement and diagnostic accuracy of a novel computer-aided detection process for the detection and prevention of retained surgical instruments. AJR Am J Roentgenol 2018; 210: 709-714.  PMID: 29446678. DOI: 10.2214/AJR.17.18576

• Balagurunathan Y, Beers A, Kalpathy-Cramer J, McNitt-Gray M, Hadjiiski L, Zhao B, Zhu J, Yang H, Yip S, Aerts H, Napel S, Cherezov D, Cha K, Chan HP, Flores C, Garcia A, Gillies R, Goldgof D. Semi-Automated Pulmonary Nodule Interval Segmentation using the NLST data. Medical Physics 2018; 45: 1093-1107.  PMCID: PMC5952359. DOI: 10.1002/mp.12766

• Li S, Wei J, Chan HP, Helvie MA, Roubidoux MA, Lu Y, Zhou C, Hadjiiski LM, Samala RK. Computer-aided assessment of breast density: Comparison of supervised deep learning and feature based statistical learning. Physics in Medicine and Biology 2018; 63: 025005. PMCID: PMC5784848. DOI: 10.1088/1361-6560/aa9f87

• Zheng J, Fessler JA, Chan HP. Detector blur and correlated noise modeling for digital breast tomosynthesis reconstruction. IEEE Trans. Medical Imaging 2018; 37: 116-127. PMCID: PMC5772655. DOI: 10.1109/TMI.2017.2732824

• Samala RK, Chan HP, Hadjiiski LM, Helvie MA, Cha KH. Richter CD. Multi-task transfer learning deep convolutional neural network: Application to computer-aided diagnosis of breast cancer on mammograms.  Physics in Medicine and Biology 2017; 62: 8894-8908. PMCID: PMC5859950. DOI: 10.1088/1361-6560/aa93d4

• Garapati SS, Hadjiiski L, Cha KH, Chan HP, Caoili EM, Cohan RH, Weizer A, Alva A, Paramagul C, Wei J, Zhou C. Urinary Bladder Cancer Staging in CT Urography using Machine Learning. Medical Physics 2017; 44:5814-5823.  PMCID:PMC5689080. DOI: 10.1002/mp.12510

• Chan HP, Helvie MA, Hadjiiski L, Jeffries DO, Klein KA, Neal CH, Noroozian M, Paramagul C, Roubidoux MA. Characterization of breast lesions in digital breast tomosynthesis and digital mammograms: an observer performance study. Academic Radiology 2017; 24: 1372-1379. PMCID: PMC5651188. DOI: 10.1016/j.acra.2017.04.016

• Cha K, Hadjiiski L, Chan HP, Weizer AZ, Alva A, Cohan RH, Caoili EM, Paramagul C, Samala RK. Bladder Cancer Treatment Response Assessment in CT using Radiomics with Deep-Learning. Scientific Reports 2017; 7: 8738. PMCID: PMC5562694. DOI: 10.1038/s41598-017-09315-w

• Lu Y, Chan HP, Wei J, Hadjiiski LM, Samala R. Improving image quality for digital breast tomosynthesis: Automated detection and diffusion-based method for metal artifact reduction. Physics in Medicine and Biology 2017; 62:7765-7783. PMCID: PMC5735824. DOI: 10.1088/1361-6560/aa8803

• Zheng J, Fessler JA, Chan HP.  Segmented Separable Footprint Projector for Digital Breast Tomosynthesis and Its application for Subpixel Reconstruction. Medical Physics 2017; 44:986-1001. PMCID: PMC5462465. DOI: 10.1002/mp.12092

• Sengupta A, Hadjiiski L, Chan HP, Cha KH, Chronis N, Marentis TC. Computer-Aided Detection of Retained Surgical Needles from Postoperative Radiographs. Medical Physics 2017; 44:180-191. PMID: 28044343. DOI: 10.1002/mp.12011

• Cha KH, Hadjiiski LM, Samala RK, Chan HP, Cohan RH, Caoili EM, Paramagul C, Alva A, Weizer AZ. Bladder Cancer Segmentation in CT for Treatment Response Assessment: Application of Deep-Learning Convolution Neural Network – A Pilot Study. Tomography 2016; 2: 421-429. PMCID: PMC5241049. DOI: 10.18383/j.tom.2016.00184

• Samala RK, Chan HP, Hadjiiski LM, Helvie MA, Wei J, Cha K. Mass Detection in Digital Breast Tomosynthesis: Deep Convolutional Neural Network with Transfer Learning from Mammography. Medical Physics 2016; 43:6654-6666.  PMCID: PMC5135717. DOI: 10.1118/1.4967345

• Samala RK, Chan HP, Hadjiiski LM, Helvie MA. Analysis of computer-aided detection techniques and signal characteristics for clustered microcalcifications on digital mammography and digital breast tomosynthesis.  Physics in Medicine and Biology 2016; 61:7092-7112.  PMCID: PMC5081259. DOI: 10.1088/0031-9155/61/19/7092

• Zhou C, Chan HP, Hadjiiski LM, Chughtai AR, Wei J, Kazerooni EA. Coronary Artery Analysis: Computer-Assisted Selection of Best-Quality Segments in Multiple-Phase Coronary CT Angiography (cCTA). Medical Physics 2016; 43: 5268-5278. PMCID: PMC5018003. DOI: 10.1118/1.4961740

• Hadjiiski LM, Liu J, Chan HP, Zhou C, Wei J, Chughtai AR, Kuriakose J, Agarwal P, Kazerooni EA.  Best-quality vessel identification using vessel quality measure in multiple-phase coronary CT angiography (cCTA). Computational and Mathematical Methods in Medicine 2016; 2016:1835297. PMCID: PMC5046098. DOI: 10.1155/2016/1835297

• Cha K, Hadjiiski L, Samala RK, Chan HP, Caoili EM, Cohan RH. Urinary Bladder Segmentation in CT Urography using Deep-Learning Convolutional Neural Network and Level Sets. Medical Physics 2016; 43:1882-1896. PMCID: PMC4808067. DOI: 10.1118/1.4944498

• Zhou C, Chan HP, Dong Q, Couriel DR, Pawarode A, Hadjiiski LM, Wei J. Quantitative analysis of MR imaging to assess treatment response for patients with multiple myeloma by using dynamic intensity entropy transformation: A preliminary study. Radiology 2016; 278:449–457. PMID:26192897. DOI: 10.1148/radiol.2015142804

• Samala RK, Chan HP, Lu Y, Hadjiiski LM, Wei J, Helvie MA. Computer-aided Detection System for Clustered Microcalcifications in Digital Breast Tomosynthesis using Joint Information from Volumetric and Planar Projection Images. Physics in Medicine and Biology 2015; 60: 8457-8479. PMCID: PMC4733604. DOI: 10.1088/0031-9155/60/21/8457

• Hadjiiski L, Weizer AZ, Alva A, Caoili EM, Cohan RH, Cha K, Chan HP. Treatment response assessment for bladder cancer on CT based on computerized volume analysis, World Health Organization criteria and RECIST. AJR Am J Roentgenol 2015; 205: 348-352. PMCID: PMC4791536. DOI: 10.2214/AJR.14.13732

• Cha K, Hadjiiski L, Chan HP, Cohan RH, Caoili EM, Zhou C. Detection of Urinary Bladder Mass in CT Urography (CTU) with SPAN. Medical Physics 2015; 42: 4271-4284. PMCID: PMC4482812. DOI: 10.1118/1.4922503

• Hadjiiski L, Marentis TC, Rondon L, Chaudhury AR, Chronis N, Chan HP.  Computer Aided Detection (CAD) of Surgical Retained Foreign Object (RFO) for Prevention. Medical Physics 2015; 42: 1213-1222. PMID: 25735276. DOI: 10.1118/1.4907964

• Stone J, Thompson DJ, Dos Santos Silva I, Scott C, Tamimi RM, Lindstrom S, Kraft P, Hazra A, Li J, Eriksson L, Czene K, Hall P, Jensen M, Cunningham J, Olson JE, Purrington K, Couch FJ, Brown J, Leyland J, Warren RM, Luben RN, Khaw KT, Smith P, Wareham NJ, Jud SM, Heusinger K, Beckmann MW, Douglas JA, Shah KP, Chan HP, Helvie MA, Le Marchand L, Kolonel LN, Woolcott C, Maskarinec G, Haiman C, Giles GG, Baglietto L, Krishnan K, Southey MC, Apicella C, Andrulis IL, Knight JA, Ursin G, Alnaes GI, Kristensen VN, Borresen-Dale AL, Gram IT, Bolla MK, Wang Q, Michailidou K, Dennis J, Simard J, Paroah P, Dunning AM, Easton DF, Fasching PA, Pankratz VS, Hopper JL, Vachon CM. Novel associations between common breast cancer susceptibility variants and risk-predicting mammographic density measures. Cancer Research. 2015; 75: 2457-2467.  Published Online First April 10, 2015; doi: 10.1158/0008-5472.CAN-14-2012. PMCID: PMC4470785. DOI: 10.1158/0008-5472.CAN-14-2012

• Lu Y, Chan HP, Wei J, Hadjiiski L, Samala RK. Multiscale Bilateral Filtering for Improving Image Quality in Digital Breast Tomosynthesis. Medical Physics 2015; 42: 182-195. PMCID: PMC4277560. DOI: 10.1118/1.4903283

• Lindström S, Thompson DJ, Paterson AD, Li J, Gierach GL, Scott C, Stone J, Douglas JA, dos-Santos-Silva I, Fernandez-Navarro P, Verghase J, Smith P, Brown J, Luben R, Wareham NJ, Loos RJ, Heit JA, Pankratz VS, Norman A, Goode EL, Cunningham JM, deAndrade M, Vierkant RA, Czene K, Fasching PA, Baglietto L, Southey MC, Giles GG, Shah KP, Chan HP, Helvie MA, Beck AH, Knoblauch NW, Hazra A, Hunter DJ, Kraft P, Pollan M, Figueroa JD, Couch FJ, Hopper JL25, Hall P, Easton DF, Boyd NF, Vachon CM, Tamimi RM.  Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk. Nature Communications. 2014; 5: 5303 (7 pages). PMCID: PMC4320806. DOI: 10.1038/ncomms6303

• Samala RK, Chan HP, Lu Y, Hadjiiski L, Wei J, Helvie M. Digital breast tomosynthesis: Computer-aided detection of clustered microcalcifications on planar projection images. Physics in Medicine and Biology 2014; 59: 7457–7477. PMCID: PMC4278849. DOI: 10.1088/0031-9155/59/23/7457

• Hadjiiski LH, Zick D, Chan HP, Cohan RH, Caoili EM, Cha KH, Zhou C, Wei J. Ureter Tracking and Segmentation in CT Urography (CTU) using COMPASS. Medical Physics 2014; 41: 121906 (10 pages). PMCID: PMC4240782. DOI: 10.1118/1.4901412

• Goodsitt MM, Chan HP, Schmitz A, Zelakiewicz S, Telang S, Hadjiiski LM, Watcharotone K, Helvie MA, Paramagul C, Neal C, Christodoulou E, Larson SC, Carson PL.  Digital breast tomosynthesis: Studies of the effects of acquisition geometry on contrast-to-noise ratio and observer preference of low-contrast objects in breast phantom images. Physics in Medicine and Biology. 2014; 59: 5883–5902. PMCID: PMC4264665. DOI: 10.1088/0031-9155/59/19/5883

• Chan HP, Goodsitt MM, Helvie MA, Zelakiewicz S, Schmitz A, Noroozian M, Paramagul C, Roubidoux MA, Nees AV, Neal C, Carson PL, Lu Y, Hadjiiski LM, Wei J. Digital breast tomosynthesis: Observer performance study of the detection of clustered microcalcifications in breast phantom images acquired with an experimental DBT system using variable scan angles, angular increments, and number of projection views. Radiology 2014; 273: 675-685. PMCID: PMC4314116. DOI: 10.1148/radiol.14132722

• Hadjiiski LM, Zhou C, Chan HP, Chughtai A, Agarwal P, Kuriakose J, Kazerooni EA. Wei J, Patel S. Coronary CT Angiography (cCTA): Automated Registration of Coronary Arterial Trees from Multiple Phases. Physics in Medicine and Biology. 2014; 59: 4661–4680. PMCID: PMC4277697. DOI: 10.1088/0031-9155/59/16/4661

• Zhou C, Chan HP, Chughtai A, Kuriakose J, Agarwal P, Kazerooni EA, Hadjiiski LM, Patel S, Wei J. Computerized analysis of coronary artery disease: performance evaluation of segmentation and tracking of coronary arteries in CT angiograms. Medical Physics 2014; 41: 081912 (11 pages). PMCID: PMC4111838. DOI: 10.1118/1.4890294

• Wei J, Zhou C, Chan HP, Chughtai A, Patel S, Agarwal P, Kuriakose J, Hadjiiski LM, Kazerooni EA. Computerized Detection of Non-calcified Plaques in Coronary CT Angiography: Evaluation of Topological Soft Gradient Prescreening Method and Luminal Analysis. Medical Physics 2014; 41: 081901 (9 pages). PMCID: PMC4105962. DOI: 10.1118/1.4885958

• Cha KH, Hadjiiski L, Chan HP, Caoili EM, Cohan RH, Zhou C. CT Urography: Segmentation of Urinary Bladder using CLASS with Local Contour Refinement. Physics in Medicine and Biology. 2014; 59: 2767-2785.  PMCID: PMC5067260. DOI: 10.1088/0031-9155/59/11/2767

• Wei J, Chan HP, Hadjiiski L, Helvie MA, Lu Y, Zhou C, Samala RK. Multi-Channel Response Analysis on 2D Projection Views for Detection of Clustered Microcalcifications in Digital Breast Tomosynthesis. Medical Physics 2014; 41: 041913 (11 pages). PMCID: PMC3971829. DOI: 10.1118/1.4868694

• Samala RK, Chan HP, Lu Y, Hadjiiski L, Wei J, Sahiner B, Helvie MA. Computer-Aided Detection of Clustered Microcalcifications in Multiscale Bilateral Filtering Regularized Reconstructed Digital Breast Tomosynthesis Volume. Medical Physics 2014; 41: 021901 (14 pages). PMCID: PMC3977832. DOI: 10.1118/1.4860955

• Henry NL, Chan HP, Dantzer J, Goswami CP, Li L, Skaar TC, Rae JM, Desta Z, Khouri N, Pinsky R, Oesterreich S, Zhou C, Hadjiiski L, Philips S, Robarge J, Nguyen AT, Storniolo AM, Flockhart DA, Hayes DF, Helvie MA, Stearns V.  Aromatase Inhibitor-Induced Modulation of Breast Density: Clinical and Genetic Effects. British Journal of Cancer. 2013;109:2331-2339. PMCID: PMC3817329. DOI: 10.1038/bjc.2013.587

• Hadjiiski LM, Chan HP, Cohan RH, Caoili EM, Law Y, Cha K, Zhou C, Wei J.  Urinary bladder Segmentation in CT urography (CTU) using CLASS. Medical Physics 2013; 40: 111906 (11 pages). PMCID: PMC3808489. DOI: 10.1118/1.4823792

• Guo Y, Zhou C, Chan HP, Chughtai AR, Wei J, Hadjiiski LM, Kazerooni EA. Automated Iterative Neutrosophic Lung Segmentation for Image Analysis in Thoracic Computed Tomography. Medical Physics 2013; 40: 081912 (11 pages). PMCID: PMC3732305. DOI: 10.1118/1.4812679

• Petrick N, Sahiner B, Armato III AG, Bert A, Correale L, Delsanto S, Freedman MT, Fryd D, Gur D, Hadjiiski L, Huo Z, Jiang Y, Morra L, Paquerault S, Raykar V, Salganicoff M, Samuelson F, Summers RM, Tourassi G, Yoshida H, Zheng B, Zhou C, Chan HP. Evaluation of Computer-aided Detection and Diagnosis Systems. Medical Physics 2013; 40: 087001 (17 pages).  PMCID: PMC4108682. DOI: 10.1118/1.4816310

• Huo Z, Summers RM, Paquerault S, Lo L, Hoffmeister J, Armato III SG, Freedman MT, Lin J, Lo SCB, Petrick N, Sahiner B, Fryd D, Yoshida H, Chan HP. Quality Assurance and Training Procedures for Computer-aided Detection and Diagnosis Systems in Clinical Use. Medical Physics 2013; 40: 077001 (13 pages). PMCID: PMC5438240. DOI: 10.1118/1.4807642

• Hadjiiski LM, Chan HP, Caoili EM, Cohan RH, Wei J, Zhou C. Auto-initialized cascaded level set (AI-CALS) segmentation of bladder lesions on multi-detector row CT urography. Academic Radiology 2013; 20:148–155.  PMCID: PMC3556363. DOI: 10.1016/j.acra.2012.08.012

• Lu Y, Chan HP, Wei J, Hadjiisk LM.  A diffusion-based truncated projection artifact reduction method for iterative digital breast tomosynthesis reconstruction. Physics in Medicine and Biology 2013; 58: 569-587.  PMCID: PMC4132954. DOI: 10.1088/0031-9155/58/3/569

• Padilla F, Roubidoux M, Paramagul C, Sinha S, Goodsitt M, LeCarpentier G, Chan HP, Hadjiiski L, Fowlkes B, Joe A, Klein K, Nees A, Noroozian M, Patterson S, Pinsky R, Hooi FM, Carson PL. Breast mass characterization using 3D automated ultrasound as an adjunct to digital breast tomosynthesis: a pilot study. Journal of Ultrasound in Medicine 2013; 32: 93-104. PMCID: PMC3556642. DOI: 10.7863/jum.2013.32.1.93

• Cho HC, Hadjiiski LM, Sahiner B, Chan HP, Helvie MA, Paramagul C, Nees AV. A similarity study of content-based image retrieval system for breast cancer using decision tree. Medical Physics 2013; 40: 012901 (13 pages). PMCID: PMC3537763. DOI: 10.1118/1.4770277

• Gallas BD, Chan HP, D’Orsi C, Dodd L, Giger M, Gur D, Krupinski EA, Metz CE, Myers KJ, Obuchowski NA, Sahiner B, Toledano A, Zuley M. Evaluating imaging and computer-aided detection and diagnosis devices at the FDA. Academic Radiology 2012; 19: 463-477. PMCID: PMC5557046. DOI: 10.1016/j.acra.2011.12.016

• Noroozian M, Hadjiiski L, Rahnama-Moghadam S, Klein KA, Jeffries DO, Pinsky RW, Chan HP, Carson PL, Helvie MA, Roubidoux MA. Digital breast tomosynthesis is comparable to mammographic spot views for mass characterization. Radiology 2012; 262: 61-68. PMCID: PMC3244671. DOI: 10.1148/radiol.11101763

• Sahiner B, Chan HP, Hadjiiski LM, Helvie MA, Wei J, Zhou C, Lu Y. Computer-aided detection of clustered microcalcifications in digital breast tomosynthesis: A 3D approach. Medical Physics 2012; 39: 28–39. PMCID: PMC3257751. DOI: 10.1118/1.3662072

• Zhou C, Chan HP, Chughtai A, Patel S, Hadjiiski LM, Wei J, Kazerooni EA. Automated coronary artery tree extraction in coronary CT angiography using a multiscale enhancement and dynamic balloon tracking (MSCAR-DBT) method. Computerized Medical Imaging and Graphics. 2012; 36: 1-10. PMCID: PMC3175011. DOI: 10.1016/j.compmedimag.2011.04.001

• Lu Y, Chan HP, Wei J, Goodsitt MM, Carson PL, Hadjiiski L, Schmitz A, Eberhard JW, Claus BEH. Image quality of microcalcifications in digital breast tomosynthesis: Effects of projection-view distributions.  Medical Physics 2011; 38: 5703-5712.  PMCID: PMC3203126. DOI: 10.1118/1.3637492

• Wei J, Chan HP, Wu YT, Zhou C, Helvie MA, Tsodikov A, Hadjiiski LM. Sahiner B. Association of computerized mammographic parenchymal pattern measure with breast cancer risk: a pilot case-control study. Radiology 2011; 260:42-49. PMCID: PMC3135878. DOI: 10.1148/radiol.11101266

• Wei J, Chan HP, Zhou C, Wu YT, Sahiner B, Hadjiiski LM. Roubidoux MA, Helvie MA. Computer-aided detection of breast masses: Four-view strategy for screening mammography. Medical Physics 2011; 38: 1867-1876.  PMCID: PMC3069993. DOI: 10.1118/1.3560462

• Cho HC, Hadjiiski LM, Sahiner B, Chan HP, Helvie MA, Paramagul C, Nees AV. Similarity Evaluation in a content-based image retrieval (CBIR) CADx system for characterization of breast masses on ultrasound images. Medical Physics 2011; 38: 1820-1831. PMCID: PMC3069991. DOI: 10.1118/1.3560877

• Hadjiiski L, Mukherji SK, Gujar S, Sahiner B, Ibrahim M, Street E, Moyer J, Chan HP.  Treatment response assessment of head and neck cancers on CT using computerized volume analysis. Amer. J. Neuroradiology 2010; 31: 1744-1751. (Selected for CME credit)  PMCID: PMC3767432. DOI: 10.3174/ajnr.A2177

• Lu Y, Chan HP, Wei J, Hadjiiski LM.  Selective-diffusion regularization for enhancement of microcalcifications in digital breast tomosynthesis reconstruction. Medical Physics 2010; 37: 6003-6014.  PMCID: PMC2988834. DOI: 10.1118/1.3505851

• Chan HP, Wu YT, Sahiner B, Wei J, Helvie MA, Zhang Y, Moore RH, Kopans DB, Hadjiiski L, Way T. Characterization of masses in digital breast tomosynthesis: comparison of machine learning in projection views and reconstructed slices. Medical Physics 2010; 37: 3576-3586. PMCID: PMC2902540. DOI: 10.1118/1.3432570

• Zhou C, Wei J, Chan HP, Paramagul C, Hadjiiski LM, Sahiner B, Douglas JA. Computerized image analysis: Texture-field orientation method for pectoral muscle identification on MLO-view mammograms. Medical Physics 2010; 37: 2289-2299. PMCID: PMC2874042. DOI: 10.1118/1.3395576

• Hadjiiski L, Mukherji SK, Ibrahim M, Sahiner B, Gujar S, Moyer J, Chan HP. Head and neck cancers on CT: preliminary study of treatment response assessment based on computerized volume analysis. AJR Am J Roentgenol 2010; 194: 1083-1089. PMCID: PMC3729396. DOI: 10.2214/AJR.09.2817

• Way T, Chan HP, Hadjiiski L, Sahiner B, Chughtai A, Song TK, Poopat C, Stojanovska J, Frank L, Attili A, Bogot N, Cascade PN, Kazerooni EA.  Computer-aided diagnosis of lung nodules on CT scans: ROC study of its effect on radiologists’ performance. Academic Radiology 2010; 17:323-332. PMCID: PMC3767437. DOI: 10.1016/j.acra.2009.10.016

• Way T, Sahiner B, Hadjiiski L, Chan HP. Effect of finite sample size on feature selection and classification: a simulation study. Medical Physics 2010; 37: 907-920. PMCID: PMC2826389. DOI: 10.1118/1.3284974

• Wu YT, Zhou C, Chan HP, Paramagul C, Zhang Y, Hadjiiski LM, Sahiner B, Shi J, Wei J.  Dynamic multiple thresholding breast boundary detection algorithm for mammograms. Medical Physics 2010; 37: 391-401. PMCID: PMC2809702. DOI: 10.1118/1.3273062

• Chan HP. Computer-Aided Diagnosis in Breast Tomosynthesis and Chest CT. Japanese J. of Radiological Technology 2009; 65: 968-976. PMCID: PMC7458208. DOI: 10.6009/jjrt.65.968

• Sahiner B, Chan HP, Hadjiiski LM, Cascade PN, Kazerooni EA, Chughtai AR, Poopat C, Song T, Frank L, Stojanovska J, Attili A. Effect of CAD on radiologists’ detection of lung nodules on thoracic CT scans: Analysis of an observer performance study by nodule size. Academic Radiology 2009; 16: 1518-1530.  PMCID: PMC2810535. DOI: 10.1016/j.acra.2009.08.006

• Shi J, Sahiner B, Chan HP, Paramagul C, Hadjiiski LM, Helvie MA, Chenevert T.  Treatment response assessment of breast masses on dynamic contrast-enhanced magnetic resonance scans using fuzzy c-means clustering and level set segmentation. Medical Physics 2009; 36: 5052-5063. PMCID: PMC2773457. DOI: 10.1118/1.3238101

• Wei J, Chan HP, Sahiner B, Zhou C, Hadjiiski LM, Roubidoux MA, Helvie MA.  Computer-aided detection of breast masses on mammograms: dual system approach with two-view analysis. Medical Physics 2009; 36: 4451-4460.  PMCID: PMC2771711. DOI: 10.1118/1.3220669

• Zhou C, Chan HP, Sahiner B, Hadjiiski LM, Chughtai A, Patel S, Wei J, Cascade PN, Kazerooni EA.  Computer-aided detection of pulmonary embolism in computed tomographic pulmonary angiography (CTPA): performance evaluation with independent data sets. Medical Physics 2009; 36: 3385-3396.  PMCID: PMC2719495. DOI: 10.1118/1.3157102

• Way T, Sahiner B, Chan HP, Hadjiiski L, Cascade P, Chughtai A, Bogot N, Kazerooni E. Computer-aided diagnosis of pulmonary nodules on CT scans: improvement of classification performance with nodule surface features. Medical Physics 2009; 36: 3086-3098. PMCID: PMC2832039. DOI: 10.1118/1.3140589

• Goodsitt MM, Chan HP, Way TW, Schipper MJ, Larson SC, Christodoulou EG. Quantitative CT of Lung Nodules: Dependence of Calibration on Patient Body Size, Lung Size and Calibration Nodule Size for Single- and Dual-Energy Techniques. Medical Physics 2009; 36: 3107-3121. PMCID: PMC2832040. DOI: 10.1118/1.3148536

• Cui J, Sahiner B, Chan HP, Nees A, Paramagul C, Hadjiiski LM, Zhou C, Shi J. A new automated method for the segmentation and characterization of breast masses on ultrasound images. Medical Physics 2009; 36: 1553-1565. PMCID: PMC2736705. DOI: 10.1118/1.3110069

• Sahiner B, Chan HP, Hadjiiski LM, Roubidoux MA, Paramagul C, Bailey JE, Nees AV, Blane CE, Adler DD, Patterson SK, Klein KA, Pinsky RW, Helvie MA. Multi-modality CADx: ROC study of the effect on radiologists' accuracy in characterizing breast masses on mammograms and 3D ultrasound images.  Academic Radiology 2009; 16: 810-818.  PMCID: PMC2722036. DOI: 10.1016/j.acra.2009.01.011

• Zhang Y, Chan HP, Sahiner B, Wei J, Zhou C, Hadjiiski LM.  Artifact reduction methods for truncated projections in iterative breast tomosynthesis reconstruction. Journal of Computer Assisted Tomography 2009; 33: 426-435. PMCID: PMC2743904. DOI: 10.1097/RCT.0b013e3181838000

• Douglas J, Roy-Gagnon MH, Zhou C, Mitchell B, Shuldiner A, Chan HP, Helvie MA.  Mammographic Breast Density – Evidence for Genetic Correlations with Established Breast Cancer Risk Factors. Cancer Epidemiology, Biomarkers and Prevention 2008; 17:3509-3516. PMCID: PMC2843541. DOI: 10.1158/1055-9965.EPI-08-0480

• Giger ML, Chan HP, Boone J. Anniversary paper: History and status of CAD and quantitative image analysis: The role of Medical Physics and AAPM. Medical Physics 2008; 35: 5799-5820. (Invited review paper)  PMCID: PMC2673617. DOI: 10.1118/1.3013555

• Filev P, Hadjiiski LM, Chan HP, Sahiner B, Ge J, Helvie MA, Roubidoux MA, Zhou C. Automated Regional Registration and Characterization of Corresponding Microcalcification Clusters on Temporal Pairs of Mammograms for Interval Change Analysis. Medical Physics 2008; 35: 5340-5350.  PMCID: PMC2736718. DOI: 10.1118/1.3002311

• Chan HP, Wei J, Zhang Y, Helvie MA, Moore RH, Sahiner B, Hadjiiski L, Kopans DB. Computer-aided detection of masses in digital tomosynthesis mammography: Comparison of three approaches. Medical Physics 2008; 35: 4087-4095. PMCID: PMC2809706. DOI: 10.1118/1.2968098

• Chan HP, Hadjiiski L, Zhou C, Sahiner B. Computer-aided diagnosis of lung cancer and pulmonary embolism in computed tomography — A review.  Academic Radiology 2008; 15: 535-555. (Invited review paper) PMCID: PMC2800985. DOI: 10.1016/j.acra.2008.01.014

• Sahiner B, Chan HP, Hadjiiski LM. Classifier performance estimation under the constraint of a finite sample size: resampling schemes applied to neural network classifiers. Neural Networks 2008; 21: 476-483. PMCID: PMC2729493. DOI: 10.1016/j.neunet.2007.12.012

• Sahiner B, Chan HP, Hadjiiski LM. Classifier performance prediction for computer-aided Diagnosis using a limited data set. Medical Physics 2008; 35: 1559-1570.  PMCID: PMC2811557. DOI: 10.1118/1.2868757

• Way TW, Chan HP, Goodsitt MM, Sahiner B, Hadjiiski LM, Zhou C, Chughtai A. Effect of CT scanning parameters on volumetric measurement of pulmonary nodules by 3D active contour segmentation: A phantom study. Physics in Medicine and Biology 2008; 53: 1295-1312. PMCID: PMC2728556. DOI: 10.1088/0031-9155/53/5/009

• Sahiner B, Chan HP, Hadjiiski LM. Performance analysis of 3-class classifiers:  Properties of the 3D ROC surface and the normalized volume under the surface for the ideal observer. IEEE Trans Medical Imaging 2008; 27: 215-227.  PMCID: PMC3023151. DOI: 10.1109/TMI.2007.905822

• Shi J, Sahiner B, Chan HP, Ge J, Hadjiiski LM, Helvie MA, Nees A, Wu YT, Wei J, Zhou C, Zhang Y, Cui J. Characterization of mammographic masses based on level set segmentation with new image features and patient information. Medical Physics 2008; 35: 280-290. PMCID: PMC2728555. DOI: 10.1118/1.2820630

• Zhou C, Chan HP, Sahiner B, Hadjiiski LM, Chungai A, Patel S, Wei J, Ge J, Cascade PN, Kazerooni EA.  Automatic multiscale enhancement and hierarchical segmentation of pulmonary vessels in CT pulmonary angiography (CTPA) images for CAD applications. Medical Physics 2007; 34: 4567-4577.  PMCID: PMC2742232. DOI: 10.1118/1.2804558

• Street E, Hadjiiski L, Sahiner B, Gujar S, Ibrahim M, Mukherji SK, Chan HP.  Automated Volume Analysis of Head and Neck Lesions on CT Scans Using 3D Level Set Segmentation. Medical Physics 2007; 34: 4399-4408. PMCID: PMC2742211. DOI: 10.1118/1.2794174

• Zhang Y, Chan HP, Sahiner B, Wu YT, Zhou C, Ge J, Wei J, Hadjiiski LM. Application of boundary detection information in breast tomosynthesis reconstruction. Medical Physics 2007; 34: 3603-3613.  PMCID: PMC2742203. DOI: 10.1118/1.2761968

• Wu YT, Wei J, Hadjiiski L, Sahiner B, Zhou C, Ge J, Shi J, Zhang Y, Chan HP.  Bilateral analysis based false positive reduction for computer-aided mass detection. Medical Physics 2007; 34: 3334-3344. PMCID: PMC2742209. DOI: 10.1118/1.2756612

• Shi J, Sahiner B, Chan HP, Hadjiiski LM, Zhou C, Cascade PN, Bogot N, Kazerooni EA, Wu YT, Wei J.  Pulmonary nodule registration in serial CT scans based on rib anatomy and nodule template matching.  Medical Physics 2007; 34: 1336-1347.  PMCID: PMC2742217. DOI: 10.1118/1.2712575

• Wei J,  Hadjiiski LM, Sahiner B, Chan HP, Ge J, Roubidoux MA, Helvie MA, Zhou C, Wu YT, Paramagul C, Zhang Y.  Computer Aided Detection Systems for Breast Masses: Comparison of Performances on Full-Field Digital Mammograms and Digitized Screen-film Mammograms. Academic Radiology 2007; 14: 659-669. PMCID: PMC2040166. DOI: 10.1016/j.acra.2007.02.017

• Ge J, Hadjiiski LM, Sahiner B, Wei J, Helvie MA, Zhou C, Chan HP.  Computer aided detection system for clustered microcalcifications: Comparison of performance on full field digital mammograms and digitized screen-film mammograms. Physics in Medicine and Biology 2007; 52: 981-1000. PMCID: PMC2742213. DOI: 10.1088/0031-9155/52/4/008

• Sahiner B, Chan HP, Roubidoux MA, Hadjiiski LM, Helvie MA, Paramagul C, Bailey JE, Nees A, Blane CE.  Malignant and benign breast masses on 3D US volumetric images: Effect of computer-aided diagnosis on radiologist accuracy. Radiology 2007; 242: 716-724. PMCID: PMC2800986. DOI: 10.1148/radiol.2423051464

• Hadjiiski LM, Chan HP, Sahiner B, Helvie MA, Roubidoux MA.  Quasi-continuous and discrete confidence rating scales for observer performance studies: Effects on ROC analysis. Academic Radiology 2007; 14: 38-48. PMCID: PMC2976672. DOI: 10.1016/j.acra.2006.09.048

• Wei J, Chan HP, Sahiner B, Hadjiiski LM, Helvie MA, Roubidoux MA, Zhou C, Ge J. Dual system approach to computer-aided detection of breast masses on mammograms. Medical Physics 2006; 33: 4157-4168. PMCID: PMC2742210. DOI: 10.1118/1.2357838

• Zhang Y, Chan HP, Sahiner B, Wei J, Goodsitt MM, Hadjiiski LM, Ge J, Zhou C. A comparative study of limited-angle cone-beam reconstruction methods for breast tomosynthesis. Medical Physics 2006; 33: 3781-3795. PMCID: PMC2728559. DOI: 10.1118/1.2237543

• Goodsitt MM, Chan HP, Way T, Larson SC, Christodoulou EG, and Kim J. Accuracy of the CT numbers of simulated lung nodules imaged with multi-detector CT scanners. Medical Physics 2006; 33:3006-3017.  PMCID: PMC2742214. DOI: 10.1118/1.2219332

• Martin KE, Helvie MA, Zhou C, Roubidoux MA, Bailey JE, Paramagul C, Blane CE, Klein K, Sonnad S, Chan HP. Mammographic density measured with quantitative computer-aided method: Comparison with radiologists’ estimates and BI-RADS categories. Radiology 2006; 240: 656-665. PMID: 16857974. DOI: 10.1148/radiol.2402041947

• Ge J, Sahiner B, Hadjiiski LM, Chan HP, Wei J, Helvie MA, Zhou C.  Computer aided detection of clusters of microcalcifications on full field digital mammograms. Medical Physics 2006; 33: 2975-2988. PMID: 16964876. DOI: 10.1118/1.2211710

• Sahiner B, Chan HP, Hadjiiski LM, Helvie MA, Paramagul C, Ge J, Wei J, Zhou C.  Joint two-view information for computerized detection of microcalcifications on mammograms. Medical Physics 2006; 33: 2574-2585.  PMCID: PMC3026322. DOI: 10.1118/1.2208919

• Way TW, Hadjiiski LM, Sahiner B, Chan HP, Cascade PN, Kazerooni EA, Bogot N, Zhou C. Computer-aided diagnosis of pulmonary nodules on CT scans: segmentation and classification using 3D active contours.  Medical Physics 2006; 33: 2323-2337. PMCID: PMC2728558. DOI: 10.1118/1.2207129

• Hadjiiski LM, Sahiner B, Helvie MA, Chan HP, Roubidoux MA, Paramagul C, Blane C, Petrick N, Bailey J, Klein K, Foster M, Patterson S, Adler D, Nees A, Shen J. Breast masses: Computer-aided diagnosis with serial mammograms. Radiology 2006; 240: 343-356. PMID: 16801362. DOI: 10.1148/radiol.2401042099

• Hadjiiski LM, Sahiner B, Chan HP.  Advances in computer-aided diagnosis for breast cancer. Current Opinion in Ostretrics and Gynecology 2006; 18: 64-70. (Invited rview paper) PMCID: PMC2800983. DOI: 10.1097/01.gco.0000192965.29449.da

• Chan HP, Wei J, Sahiner B, Rafferty EA, Wu T, Roubidoux MA, Moore RH, Kopans DB, Hadjiiski LM, Helvie MA. Computer-aided detection system for breast masses on digital tomosynthesis mammograms: Preliminary experience. Radiology 2005; 237:1075-1080. PMCID: PMC2800984. DOI: 10.1148/radiol.2373041657

• Partain CL, Chan HP, Gelovani JG, Giger, ML, Izatt JA, Jolesz FA, Kandarpa K, Li KCP, McNitt-Gray M, Napel S, Summers RM, Gazelle GS,. Biomedical Imaging Research Opportunities Workshop II:  Report and Recommendations. Radiology 2005; 236: 389-403. PMID: 16040898. DOI: 10.1148/radiol.2362041876

• Ge Z, Sahiner B, Chan HP, Hadjiiski LM, Cascade PN, Bogot N, Kazerooni EA, Wei J, Zhou C. Computer aided detection of lung nodules: false positive reduction using a 3D gradient field method and 3D ellipsoid fitting. Medical Physics 2005; 32: 2443-2454. PMCID: PMC2800987. DOI: 10.1118/1.1944667

• Wei J, Sahiner B, Hadjiiski LM, Chan HP, Petrick N, Helvie MA, Roubidoux MA, Ge J, Zhou C. Computer-aided detection of breast masses on full field digital mammograms. Medical Physics 2005; 32: 2827-2838. PMCID: PMC2742215. DOI: 10.1118/1.1997327

• Zhou C, Chan HP, Patel S, Cascade PN, Sahiner B, Hadjiiski LM, Kazerooni EA. Preliminary investigation of computer-aided detection of pulmonary embolism in 3D computed tomographic pulmonary angiography (CTPA) images. Academic Radiology 2005; 12:782-792.  PMCID: PMC2784697. DOI:10.1016/j.acra.2005.01.014

• Chan HP, Goodsitt MM, Helvie MA, Hadjiiski LM, Lydick JT, Roubidoux MA, Bailey JE, Nees A, Blane CE, Sahiner B. ROC study of the effect of stereoscopic imaging on assessment of breast lesions. Medical Physics 2005; 32: 1001-1009. PMID: 15895583 DOI: 10.1118/1.1870172

• Filev P, Hadjiiski L, Sahiner B, Chan HP, Helvie MA. Comparison of similarity measures for the task of template matching of masses on serial mammograms. Medical Physics 2005; 32: 515-529. PMID: 15789598. DOI: 10.1118/1.1851892

• Kapur A, Carson PL, Eberhard J, Goodsitt MM, Thomenius K, Lokhandwalla M, Buckley D, Roubidoux MA, Helvie MA, Booi RC, LeCarpentier GL, Erkamp RQ, Chan HP, Fowlkes JB, Thomas JA, Landberg CE.  Combination of digital mammography with semi-automated 3D breast ultrasound. Technology in Cancer Research and Treatment 2004; 3(4): 325-334. PMCID: PMC2921830. DOI:10.1177/153303460400300402

• Zhou C, Chan HP, Paramagul C, Roubidoux MA, Sahiner B, Hadjiiski LM, Petrick N. Computerized nipple identification for multiple image analysis in computer-aided diagnosis. Medical Physics 2004; 31: 2871-2882. PMCID: PMC2898150. DOI: 10.1118/1.1800713

• Goodsitt MM, Chan HP, Lydick JT, Gandra CR, Chen NG, Helvie MA, Bailey J, Roubidoux MA, Blane CE, Sahiner B, Petrick N. An observer study comparing spot imaging regions selected by radiologists and a computer for an automated stereo spot mammography technique. Medical Physics 2004; 31: 1558-1567. PMID: 15259660. DOI: 10.1118/1.1737492

• Hadjiiski L, Chan HP, Sahiner B, Helvie MA, Roubidoux MA, Blane C, Paramagul C, Petrick N, Bailey J, Klein K, Foster M, Patterson S, Adler D, Nees A, Shen J. Improvement in radiologists’ characterization of malignant and benign breast masses on serial mammograms with computer-aided diagnosis: An ROC study.  Radiology 2004; 233: 255-265. PMID: 15317954. DOI: 10.1148/radiol.2331030432

• Dodd LE, Wagner RF, Armato SG III, McNitt-Gray MF, Beiden S, Chan HP, Gur D, McClennan G, Metz CE, Petrick N, Sahiner B, Sayre J. and the LIDC research group. Assessment methodologies and statistical issues for computer-aided diagnosis of lung nodules in CT: Contemporary research topics relevant to the Lung Image Database Consortium. Academic Radiology 2004; 11: 462-475. DOI: 10.1016/s1076-6332(03)00814-6

• Milne EN, Krupinski EA, Helvie MA, Hadjiiski L, Chan HP. Computer-aided detection of breast cancer.  Radiology 2004; 233:615-616, author reply 616-617. PMID: 15516624. DOI: 10.1148/radiol.2332040627

• Helvie MA, Hadjiiski L, Makariou E, Chan HP, Petrick N, Sahiner B, Lo SCB, Freedman M, Adler D, Bailey J, Blane C, Hoff D, Hunt K, Joynt L, Klein K, Paramagul C, Patterson S, Roubidoux MA. Sensitivity of noncommercial computer-aided detection system for mammographic breast cancer detection: Pilot clinical trial. Radiology 2004; 231: 208-214. PMCID: PMC2742201 DOI: 10.1148/radiol.2311030429

• Wei J, Chan HP, Helvie MA, Roubidoux MA, Sahiner B, Hadjiiski L, Zhou C, Paquerault S, Chenevert T, Goodsitt MM. Correlation between Mammographic Density and Volumetric Fibroglandular Tissue Estimated on Breast MR Images. Medical Physics 2004; 31: 933-942. PMID: 15125012 DOI: 10.1118/1.1668512

• Sahiner B, Chan HP, Roubidoux MA, Helvie MA, Hadjiiski LM, Ramachandran A, Paramagul C, LeCarpentier GL, Nees A, Blane C. Computerized Characterization of Breast Masses on 3D Ultrasound Volumes. Medical Physics 2004; 31: 744-754. DOI: 10.1118/1.1649531

• Gur D, Wagner RF, Chan HP. On the Repeated Use of Databases for Testing Incremental Improvement of CAD Schemes. (Perspective) Academic Radiology 2004; 11: 103-105. DOI: 10.1016/s1076-6332(03)00511-7

• Chan HP, Goodsitt MM, Hadjiiski LM, Bailey JE, Klein K, Darner KL, Sahiner B. Effects of Magnification and Zooming on Depth Perception in Digital Stereomammography: An Observer Performance Study. Physics in Medicine and Biology 2003; 48: 3721-3734. DOI: 10.1088/0031-9155/48/22/007

• Christodoulou EG, Goodsitt MM, Larson SC, Darner KL, Satti J, Chan HP. Evaluation of the transmitted exposure through lead equivalent aprons used in a Radiology Department, including the contribution from backscatter. Medical Physics 2003; 30: 1033-1038. DOI: 10.1118/1.1573207

• Goodsitt MM, Chan HP, Darner KL, Hadjiiski LM. The effects of stereo shift angle, geometric magnification, and display zoom on depth measurements in digital stereomammography. Medical Physics 2002; 29: 2725-2734. DOI: 10.1118/1.1517615

• Gurcan MN, Sahiner B, Petrick N, Chan HP, Kazerooni EA, Cascade PN, Hadjiiski LM. Lung nodule detection on thoracic CT images: Preliminary evaluation of a computer-aided diagnosis system. Medical Physics 2002; 29: 2552-2558. DOI: 10.1118/1.1515762

• Petrick N, Sahiner B, Chan HP, Helvie MA, Paquerault S, Hadjiiski LM. Breast cancer detection: Evaluation of a mass detection algorithm for computer-aided diagnosis – Experience in 263 patients. Radiology 2002; 224: 217-224. DOI: 10.1148/radiol.2241011062

• Gurcan MN, Chan HP, Sahiner B, Hadjiiski LM, Petrick N, Helvie MA. Optimal neural network architecture selection: Improvement in computerized detection of microcalcifications. Academic Radiology 2002; 9: 420-429. DOI: 10.1016/s1076-6332(03)80187-3

• Paquerault S, Petrick N, Chan HP, Sahiner B, Helvie MA.  Improvement of Computerized Mass Detection on Mammograms: Fusion of Two-View Information. Medical Physics 2002; 29: 238-247. DOI:10.1118/1.1446098

• Sahiner B, Petrick N, Chan HP, Hadjiiski LM, Paramagul C, Helvie MA, Gurcan MN. Computer-aided characterization of mammographic masses: accuracy of mass segmentation and its effects on characterization. IEEE Trans Medical Imaging 2001; 20: 1275-1284. DOI: 10.1109/42.974922

• Hadjiiski L, Sahiner B, Chan HP, Petrick N, Helvie MA, Gurcan MN. Analysis of Temporal Change of Mammographic Features: Computer-Aided Classification of Malignant and Benign Breast Masses. Medical Physics. 2001; 28: 2309-2317. DOI: 10.1118/1.1412242

• Gurcan MN, Sahiner B, Chan HP, Hadjiiski LM, Petrick N. Selection of an Optimal Neural Network Architecture for Computer-aided Detection of Microcalcifications – Comparison of Automated Optimization Techniques. Medical Physics 2001; 28: 1937-1948. DOI: 10.1118/1.1395036

• Beiden SV, Wagner RF, Campbell G, Chan HP. Analysis of uncertainties in estimates of components of variance in multivariate ROC analysis. Academic Radiology 2001; 8: 616-622. DOI: 10.1016/S1076-6332(03)80686-4

• Sahiner B, Chan HP, Petrick N, Helvie MA, Hadjiiski LM.  Improvement of mammographic mass characterization using spiculation measures and morphological features. Medical Physics 2001; 28: 1455-1465. DOI: 10.1118/1.1381548

• Zhou C, Chan HP, Petrick N, Helvie MA, Goodsitt MM, Sahiner B, Hadjiiski LM. Computerized image analysis: Estimation of breast density on mammograms. Medical Physics 2001; 28: 1056-1069. PMID: 11439475. DOI: 10.1118/1.1376640

• Hadjiiski LM, Chan HP, Sahiner B, Petrick N, Helvie MA.  Automated registration of breast lesions in temporal pairs of mammograms for interval change analysis – local affine transformation for improved localization. Medical Physics 2001; 28: 1070-1079. DOI: 10.1118/1.1376134

• Chan HP, Helvie MA, Petrick N, Sahiner B, Adler DD, Paramagul C, Roubidoux MA, Blane CE, Joynt LK, Wilson TE, Hadjiiski LM, Goodsitt MM.  Digital mammogramphy: observer performance study of effects of pixel size on radiologists' characterization of malignant and benign microcalcifications. Academic Radiology 2001; 8: 454-466. DOI: 10.1016/S1076-6332(03)80616-5

• Christodoulou EG, Goodsitt MM, Chan HP, Hepburn TW.  Phototimer setup for CR imaging. Medical Physics 2000; 27: 2652-2658. DOI: 10.1118/1.1319522

• Guest AR, Helvie MA, Chan HP, Hadjiiski LM, Bailey JE, Roubidoux MA.  Adverse effects of increased body weight on quantitative measures of mammographic image quality. Am. J. Roentgenol. 2000; 175: 805-810. DOI: 10.2214/ajr.175.3.1750805

• Sahiner B, Chan HP, Petrick N, Wagner RF, Hadjiiski LM.  Feature selection and classifier performance in computer-aided diagnosis: the effect of finite sample size.  Medical Physics 2000; 27: 1509-1522. DOI:10.1118/1.599017

• Goodsitt MM, Chan HP, Hadjiiski LM.  Stereomammography: Evaluation of depth perception using a virtual 3D cursor.  Medical Physics 2000; 27: 1305-1310. DOI: 10.1118/1.599008

• Hadjiiski LM, Sahiner B, Chan HP, Petrick N, Helvie MA.  Classification of malignant and benign masses based on hybrid ART2LDA approach.  IEEE Trans. Medical Imaging 1999; 18: 1178-1187. DOI:10.1109/42.819327

• Sanjay-Gopal S, Chan HP, Wilson TE, Helvie MA, Petrick N, Sahiner B.  A regional registration technique for automated interval change analysis of breast lesions on mammograms.  Medical Physics 1999; 26: 2669-2679. DOI: 10.1118/1.598806

• Carlsson GA, Chan HP.  Commentary: progress in optimization of patient dose and image quality in x-ray diagnostics. Physics in Medicine and Biology 1999; 44 (2): U3-U4. DOI: 10.1088/0031-9155/44/2/001

• Chan HP, Sahiner B, Wagner RF, Petrick N.  Classifier design for computer-aided diagnosis:  Effects of finite sample size on the mean performance of classical and neural network classifiers.  Medical Physics 1999; 26: 2654-2668. DOI: 10.1118/1.598805

• Chan HP, Sahiner B, Helvie MA, Petrick N, Roubidoux MA, Wilson TE, Adler DD, Paramagul C, Newman JS, Sanjay-Gopal S.  Improvement of radiologists' characterization of mammographic masses by computer-aided diagnosis: an ROC Study.   Radiology 1999; 212: 817-827. DOI: 10.1148/radiology.212.3.r99au47817

• Keshavmurthy SP, Goodsitt MM, Chan HP, Helvie MA.  Design and evaluation of an external filter technique for exposure equalization in mammography.  Medical Physics 1999; 26: 1655-1669. DOI:10.1118/1.598659

• Petrick N, Chan HP, Sahiner B, Helvie MA, Goodsitt MM.  Combined adaptive enhancement and object-based region growing for automated detection of masses on mammograms.  Medical Physics 1999; 26: 1642-1654. DOI: 10.1118/1.598658

• Chan HP, Sahiner B, Lam KL, Petrick N, Helvie MA, Goodsitt MM, Adler DD.  Computerized analysis of mammographic microcalcifications in morphological and texture feature spaces.  Medical Physics 1998; 25: 2007-2019. DOI: 10.1118/1.598389

• Sahiner B, Chan HP, Petrick N, Helvie MA, Goodsitt MM.  Design of a high-sensitivity classifier for computer-aided diagnosis: Application to computer-aided diagnosis. Physics in Medicine and Biology 1998; 43: 2853-2871. DOI: 10.1088/0031-9155/43/10/014

• Goodsitt MM, Chan HP, Liu B, Morton AR, Guru SV, Keshavmurthy S, Petrick N.  Classification of compressed breast shape for the design of equalization filters in x-ray mammography.  Medical Physics 1998; 25: 937-948. DOI: 10.1118/1.598272

• Sahiner B, Chan HP, Petrick N, Helvie MA, Goodsitt MM.  Computerized characterization of masses on mammograms:  The rubber-band straightening transform and texture analysis.  Medical Physics 1998; 25: 516-526. DOI: 10.1118/1.598228

• Wei D, Chan HP, Petrick N, Sahiner B, Helvie MA, Adler DD, Goodsitt MM.  False-positive reduction technique for detection of masses on digital mammograms: global and local multiresolution texture analysis.  Medical Physics 1997; 24: 903-914. DOI: 10.1118/1.598011

• Goodsitt MM, Chan HP, Liu B.  Investigation of the line-pair pattern method for evaluating mammographic focal spot performance.  Medical Physics 1997; 24: 11-15. DOI: 10.1118/1.597921

• Chan HP, Sahiner B, Petrick N, Helvie MA, Lam KL, Adler DD, Goodsitt MM.  Computerized classification of malignant and benign microcalcifications on mammograms: Texture analysis using artificial neural network.  Physics in Medicine and Biology 1997; 42: 549-567. DOI: 10.1088/0031-9155/42/3/008

• Sahiner B, Chan HP, Petrick N, Wei D, Helvie MA, Adler DD, Goodsitt MM.  Image feature selection by a genetic algorithm:  Application to classification of mass and normal breast tissue on mammograms.  Medical Physics 1996; 23: 1671-1684. DOI: 10.1118/1.597829

• Sahiner B, Chan HP, Petrick N, Wei D, Helvie MA, Adler DD, Goodsitt MM.  Classification of mass and normal breast tissue: A convolution neural network classifier with spatial domain and texture images.  IEEE Trans. Medical Imaging 1996; 15: 598-610. DOI: 10.1109/42.538937

• Petrick N, Chan HP, Wei D, Sahiner B, Helvie MA, Adler DD.  Automated detection of breast masses on mammograms using adaptive contrast enhancement and tissue classification.  Medical Physics 1996; 23: 1685-1696. DOI: 10.1118/1.597756

• Chan HP, Lo SCB, Niklason LT, Ikeda DM, Lam KL.  Image compression in digital mammography:  Effects on computerized detection of subtle microcalcifications. Medical Physics 1996; 23: 1325-1336. DOI:10.1118/1.597871

• Petrick N, Chan HP, Sahiner B, Wei D.  An adaptive density weighted contrast enhancement filter for mammographic breast mass detection.  IEEE Trans. Medical Imaging 1996; 15: 59-67. DOI:10.1109/42.481441

• Lo SCB, Chan HP, Lin JS, Li H, Freedman M, Mun SK.  Artificial Convolution neural network for medical image pattern recognition.  Neural Networks 1995; 8: 1201-1214. DOI: 10.1016/0893-6080(95)00061-5

• Chan HP, Lo SCB, Sahiner B, Lam KL, MA Helvie.  Computer-aided detection of mammographic microcalcifications: Pattern recognition with an artificial neural network.  Medical Physics 1995; 22: 1555-1567. DOI: 10.1118/1.597428

• Liu B, Goodsitt MM, Chan HP.  Normalized average glandular dose in magnification mammography.  Radiology 1995; 197: 27-32. DOI: 10.1148/radiology.197.1.7568836

• Wei D, Chan HP, Helvie MA, Sahiner B, Petrick N, Adler DD, Goodsitt MM.  Classification of mass and normal breast tissue on digital mammograms: Multiresolution texture analysis.  Medical Physics 1995; 22: 1501-1513. DOI: 10.1118/1.597418

• Chan HP, Wei D, Helvie MA, Sahiner B, Adler DD, Goodsitt MM, Petrick N.  Computer-aided classification of mammographic masses:  Linear discriminant analysis in texture feature space.  Physics in Medicine and Biology 1995; 40: 857-876. DOI: 10.1088/0031-9155/40/5/010

• Cheng SNC, Chan HP, Helvie MA, Goodsitt MM, Adler DD, St. Clair DC.  Classification of mass and non-mass regions on mammograms using artificial neural network.  J. of Imaging Science & Technology 1994; 38: 598-603.

• Goodsitt MM, Hepburn T, Cascade PN, Chan HP.  Solarization in Clinical Imaging.  Radiology.1994; 193: 871-874. DOI: 10.1148/radiology.193.3.7972839

• Helvie MA, Chan HP, Adler DD, Boyd PG.  Breast thickness in routine mammograms: Effect on image quality and radiation dose.  AJR Am J Roentgenol 1994; 163: 1371-1374. DOI: 10.2214/ajr.163.6.7992731

• Petrosian A, Chan HP, Helvie MA, Goodsitt MM, Adler DD.  Computer-aided diagnosis in mammography: classification of masses and normal tissue by texture analysis.  Physics in Medicine and Biology 1994; 39: 2273-2288. DOI: 10.1088/0031-9155/39/12/010

• Niklason LT, Marx MV, Chan HP, Webster EW.  The estimation of occupational effective dose in diagnostic radiology with two dosimeters.  Health Physics 1994; 67: 611-615. DOI: 10.1097/00004032-199412000-00003

• Cheng SNC, Chan HP, Niklason LT, Adler RS.  Automated segmentation of regions of interest on hand radiographs for texture analysis.  Medical Physics 1994; 21: 1293-1300. DOI: 10.1118/1.597402

• Niklason LT, Chan HP.  Evaluation of a parallel hole grid for bedside chest imaging.  Investigative Radiology 1994; 29: 682-688. DOI: 10.1097/00004424-199407000-00004

• Chan HP, Niklason LT, Ikeda DM, Lam KL, Adler DD.  Digitization requirements in mammography: Effects on computer-aided detection of microcalcifications. Medical Physics 1994; 21; 1203-1211. DOI:10.1118/1.597354

• Chang CL, Chan HP, Niklason LT, Cobby M, Crabbe J, Adler RS.  Computer-aided diagnosis: Detection and characterization of hyperparathyroidism in digital hand radiographs.  Medical Physics 1993; 20: 983-992. DOI: 10.1118/1.596980

• Niklason LT, Marx MV, Chan HP.  Interventional Radiologists:  Occupational effective dose and radiation risk.  Radiology 1993; 187: 729-733. DOI: 10.1148/radiology.187.3.8497622

• Niklason LT, Chan HP, Cascade PN, Chang CL, Chee P, Mathews JF.  Portable chest imaging: Comparison of storage phosphor digital system, asymmetric screen/film system and conventional screen/film system.  Radiology 1993; 186: 387-393. DOI: 10.1148/radiology.186.2.8421740 

• Chan HP, Doi K, Vyborny CJ, Schmidt RA, Metz CE, Lam KL, Ogura T, Wu Y, MacMahon H.  Improvement in radiologists' detection of clustered microcalcifications on mammograms: The potential of computer-aided diagnosis.  Investigative Radiology 1990; 25: 1102-1110. DOI: 10.1097/00004424-199010000-00006

• Hoffmann KR, Doi K, Chen SH, Chan HP.  Automated tracking and computer reproduction of vessels in DSA images.  Investigative Radiology 1990; 25: 1069-1075. DOI: 10.1097/00004424-199010000-00001

• Chan HP, Lam KL, Wu Y.  Studies of performance of antiscatter grids in digital radiography: Effect on signal-to-noise ratio.  Medical Physics 1990; 17: 655-664. DOI: 10.1118/1.596496

• Lam KL, Chan HP, MacMahon H, Oravecz WT, Doi K.  Dynamic digital subtraction evaluation of regional pulmonary ventilation with non-radioactive xenon.  Investigative Radiology 1990; 25: 728-735. DOI:10.1097/00004424-199006000-00021

• MacMahon H, Doi K, Chan HP, Giger ML, Katsuragawa S, Nakamori N.  Computer-aided diagnosis in Chest Radiology.  Journal of Thoracic Imaging 1990; 5: 67-76. DOI: 10.1097/00005382-199001000-00011

• Lam KL, Chan HP.  Effects of x-ray beam equalization on mammographic imaging.  Medical Physics 1990; 17: 242-249. DOI: 10.1118/1.596502

• Lam KL, Chan HP.  Exposure equalization technique in mammography.  Investigative Radiology 1989; 24: 154-157. DOI: 10.1097/00004424-198902000-00013

• Metz CE, Chan HP, Doi K, Shen JH.  Contrast enhancement of noisy images by windowing: Limitations due to the finite dynamic range of the display system.  Medical Physics 1989; 16: 170-178. DOI:10.1118/1.596369